CONFIDE
Symptom Impact and Experience
Key findings from the CONFIDE US dataset:
- Data collected included perspectives on the experience and impact of symptoms in patients with moderate-to-severe ulcerative colitis (UC)1
- To identify symptoms, patients were asked to select from a list of 30 symptoms, some of which include: diarrhea, bowel urgency, increased stool frequency, urge incontinence, persistent abdominal pain, and bowel urgency related accidents.1-4
- Diarrhea, bowel urgency, and increased stool frequency were experienced by most patients with UC1
- Bowel urgency and fear of urge incontinence were the most reported symptoms leading patients declining participation in social events, sports/physical exercise, and work/school2
- A large proportion of the surveyed patients reported wearing diapers/pads/protection in the past three months due to fear/anticipation of urge incontinence3
- More than three quarters of female patients and more than half of male patients reported avoiding or decreasing sexual activity due to their UC4
Symptoms ever suffered from
Symptoms currently suffering from
Patient survey questions
1. Which symptoms do you currently suffer from (that is over the last month)?
2. Which symptoms have you ever suffered from?
The top 3 current (last month) or ever suffered symptoms were diarrhea, bowel urgency, and increased stool frequency. Blood in stool was reported as ever occurring by 51.0% (n=102) and currently occurring by 27.0% (n=54), data not shown. Patients selected symptoms from a list of 30 options.
Use of diapers, pads or other protection in the last three months due to fever/anticipation of bowel-urgency related accident 
Patients who declined participation in activites in the past 3 months due to bowel urgency
Among patients who reported avoiding or decreased sexual activity (n=126), top reasons for avoiding sexual activity in the past 3 months 
Related resources
Communicating Needs and Features of IBD Experiences (CONFIDE) Study: Key results for US patients with ulcerative colitis
This infographic summarizes the key results of the CONFIDE study for patients with moderate-to-severe ulcerative colitis in the United States.
Communicating Needs and Features of Inflammatory Bowel Disease Experiences (CONFIDE) Study Summary
This infographic summarizes the background, development, and design of the CONFIDE study.
References
- Rubin DT, Panaccione R, Potts Bleakman A, et al. P028 Communicating needs and features of IBD experiences (CONFIDE) Survey: Patient and health care professional perspectives on experience of ulcerative colitis symptoms. Am J Gastroenterol. 2021;116(Suppl 1):S7.
- Dubinsky MC, Schreiber S, Potts Bleakman A, et al. P087 Communicating needs and features of IBD experiences (CONFIDE) Survey: Impact of ulcerative colitis symptoms on daily life. J Crohns Colitis. 2022;16(Suppl 1):i186-i187.
- Schreiber S, Travis S, Potts Bleakman A, et al. Communicating Needs and Features of IBD Experiences (CONFIDE) Survey: Burden and impact of bowel urgency on patients with moderate to severe ulcerative colitis. Inflamm Bowel Dis. 2022;28 (Suppl. 1):S79.
- Travis S, Dubinsky MC, Schreiber S, et al. Communicating Needs and Features of IBD Experiences (CONFIDE) Survey: Impact of moderately to severely active ulcerative colitis on sexual activity. Gastroenterology 2022;162(suppl):232.
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